Freedom (Part 1) This is the first hour of a 2-hour season finale. A two episode entries have been created. The 10pm EST marker will mark to beginning of the second episode. A couple undergoes surgery. Derek and Meredith clinical trial has another patient. Izzie helps Alex. McSteamy hooks up with someone. Freedom (Part 2) This is the second hour of a 2-hour season finale. A two episode entries have been created. The 10pm EST marker will mark to beginning of the second episode. A couple undergoes surgery. Derek and Meredith clinical trial has another patient. Alex breaks down for the first time ever. Izzie offers a friend some help. McSteamy hooks up with someone. A new couple appears. Lexie gets something unexpectedly. George gets a second chance.
Dr. Wyatt refuses to let Meredith give up on therapy. Alex learns something else about Rebecca. The Chief wants Erica to perform a daring surgery. Cristina continues to act strange.
The clinical trial continues to make progress. The anti-McSteamy club creates new initiatives but that isn't enough to stop one woman from spending time with him. Cristina is affected by Burke's career developments.
Addison visits Seattle Grace because they need skills that only she has. Rebecca/Ava returns with news for Alex. Meredith and Derek's clinical trial experiences one or two developments.
Time, specifically six weeks, has passed but sexual angst still runs rampant in the halls of Seattle Grace. Derek and Rose have been dating. Meredith has noticed the activities of her current off-again ex-boyfriend. George and Lexie are getting used to their new apartment. The doctors are in the midst of a competition when a man arrives at the hospital after having survived an attack by a bear. Erica Hahn makes a friend.
George has a surprise visitor. Callie copes with not being an O'Malley anymore. Bailey's family is falling apart, by her husband not thinking she cares about her son and husband. Tuck goes into surgery with the whole hospital worried. Derek sorts through what kissing Rose means. Meredith discovers something that doesn't inspire hope or happiness in her. Alex treats a faith healer, and doesn't believe in her "powers".
An ambulance crash endangers the lives of the paramedics involved, as Meredith and the Chief work on-site to save them, Bailey treats a patient who refuses her help, and Ava returns for Alex and meets his other girlfriend in the process.
There has been a bus crash and the patients are in the ER. Meredith and Derek's relationship gets more complicated when he dates a fellow doctor. Meredith's dad visits her at the hospital.
Two arguing parents, who are named Jane and Don, bring their son in because he swallowed marbles, while a middle aged woman comes in wanting cosmetic surgery on her chin. A father worries about raising a child alone when the mother needs surgery.
Cristina and Izzie are fighting for surgeries and a favor from someone. A patient comes to the ER with a dream and a condition which may prevent him from realizing it. The Chief turns to the other men in the hospital when his marriage is in more trouble. Two patients are competing to win something big. One of them convinces an intern to take their place.
